This video delves into the underlying mechanisms, symptoms, lifestyle and treatment associated with chronic fatigue syndrome. The purpose of this video is to educate a general audience about chronic fatigue syndrome, its diagnosis, and treatment (or lack of treatment options).

Please look at the following links to gain more information:

PACE trial reanalysis: https://t.co/aPGuX9aIpg and https://t.co/as6cZKsf6h
PACE trail: https://www.ncbi.nlm.nih.gov/pubmed/21334061

This video was made by Demystifying Medicine students: Sabrina Garritano, Angelica Dimita, Hayley Duff, and Desmond Chan

Copyright McMaster University 2018

References

Courage, K. H. (2014). Baffling chronic fatigue syndrome set for diagnostic overhaul. Scientific American. Retrieved from https://www.scientificamerican.com/article/baffling-chronic-fatigue-syndrome-set-for-diagnostic-overhaul/

Lorusso, L., Mikhalova, S. V., Capelli, E., Ferrari, D., Ngonga, G. K., & Ricevuti, G. (2008). Immunological aspects of chronic fatigue syndrome. Autoimmunity Reviews. doi:i:10.1016/j.autrev.2008.08.003

Mayo Clinic. (2018). Chronic fatigue syndrome. Retrieved from https://www.mayoclinic.org/diseases- conditions/chronic-fatigue-syndrome/symptoms-causes/syc-20360490

Mayo Clinic. (2018, January 05). Chronic fatigue syndrome – Diagnosis and Treatment. Retrieved March 19, 2018, from https://www.mayoclinic.org/diseases-conditions/chronic-fatigue-syndrome/diagnosis-treatment/drc-20360510

O’Rourke, M. (2015). A new name, and wider recognition, for chronic fatigue syndrome. The New Yorker. Retrieved from https://www.newyorker.com/tech/elements/chronic-fatigue-syndrome- iom-report

White, P. D., Goldsmith, K. A., Johnson, A. L., Potts, L., Walwyn, R., DeCesare, J. C., … & Bavinton, J. (2011). Comparison of adaptive pacing therapy, cognitive behaviour therapy, graded exercise therapy, and specialist medical care for chronic fatigue syndrome (PACE): a randomised trial. The Lancet, 377(9768), 823-836.

Rehmeyer, J., & Tuller, D. (2017). Getting it wrong on chronic fatigue syndrome. The New York Times. Retrieved from https://www.nytimes.com/2017/03/18/opinion/sunday/getting-it-wrong-on-chronic-fatigue-syndrome.html

Rowe, P. C., Underhill, R. A., Friedman, K. J., Gurwitt, A., Medow, M. S., Schwartz, M. S., … & Rowe, K. S. (2017). Myalgic encephalomyelitis/chronic fatigue syndrome diagnosis and management in young people: a primer. Frontiers in pediatrics, 5, 121.

Wilshire, C., Kindlon, T., Matthees, A., & McGrath, S. (2017). Can patients with chronic fatigue syndrome really recover after graded exercise or cognitive behavioural therapy? A critical commentary and preliminary re-analysis of the PACE trial. Fatigue: Biomedicine, Health & Behavior, 5(1), 43-56.

Yancey, J. R., & Thomas, S. M. (2012). Chronic fatigue syndrome: diagnosis and treatment. Am Fam Physician, 86(8), 741-746.

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