Psilocybin may ‘reset’ the brain to help manage treatment-resistant depression



Freely access the full article here: https://go.nature.com/Psilocybin

Robin L Carhart-Harris, Leor Roseman, Mark Bolstridge, Lysia Demetriou, J Nienke Pannekoek, Matthew B Wall, Mark Tanner, Mendel Kaelen, John McGonigle, Kevin Murphy, Robert Leech, H Valerie Curran & David J Nutt “Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms.” Scientific Reports 2017.

https://go.nature.com/Psilocybin

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46 thoughts on “Psilocybin may ‘reset’ the brain to help manage treatment-resistant depression

  1. LMFAO! I always told my friends that it "recharged my emotional batteries". I got chills when the video said "essentially disintegrated and reintegrated the network". Perfect description! I try to do it once a year. PLEASE TAKE CARE OF YOUR MENTAL HEALTH EVERYBODY!

  2. I am looking for medical sponcership as a test subject to get treated with 🍄 for anxiety and panic attacks as part of research subject, can anyone please suggest how find a medical sponcer? Clinical Trial

  3. About those who identify with the racist legal construct of so-called whiteness who’re insufferably cringe clueless about the impunity only they are granted and ranting and raving about it because of the false consciousness they’re afforded in their unnecessary racialized hierarchy: It’s a massive kick in the teeth to people who don’t identify with the racist legal construct of “whiteness” & especially indigenous people, because it’s (psychedelics) been integral to indigenous belief systems for thousands of years (and colonizers are disrespecting it and the land trying to find it), but also, those who the police don’t discern identify as the racist legal construct of “whiteness” (nonwhite), are by no means getting the same impunity as those who do, and that is proven through vast preponderance of antecedent evidence and it is an absolute ongoing crime against humanity, so they’re unfortunately not going to be treated fairly and still are not treated fairly. The “white” people who are granted impunity by their structurally racist and structurally corrupt coercive monopoly of the state a.k.a. police enforced unnecessary racialized settler colonialist social dominance hierarchy since Columbus ranting and raving about the impunity they are granted, it’s really disillusioning, it’s indicative of the false consciousness they are afforded in the hierarchy they create, maintain and enforce, and it’s really a kick in the teeth. I wish it wasn’t so but it just is😒
    They stole the land from the indigenous through genocide to pay for their structurally racist and structurally corrupt coercive monopoly of the state 😒😭🤦🏽‍♂️🤦🏽‍♂️

  4. Sounds of a Seminole I saw the size 9 recreational edible marijuana medicinal use LSD coyote syllabus Garden MDMA 9 recreational cocaine without cutting all full of a sidon non-recreational edible marijuana THC and CBD non recreational edible marijuana syllabus guide magic mushrooms I like the coyote marijuana magic mushrooms ecstasy coyote edible marijuana cocaine on recreational lsd90 commercial coyote operation edible weeds magic mushrooms

  5. I APPRECIATE THE RECOMMENDATIONS I SAW HERE HE'S TRULY AS GOOD AS YOU'LL SAY ——————————————————————————————————————————————————————————————————————————————————————————————————————————- You can reach out to this dude myco.spor on Instagram I ordered from . He sells psychedelics discreetly, hove Mushroom Embryos, shrooms, Dmt , Lsd and more 🍄💯 he could direct you also on how to microdos 🤩🍄💯

  6. I APPRECIATE THE RECOMMENDATIONS I SAW HERE HE'S TRULY AS GOOD AS YOU'LL SAY ——————————————————————————————————————————————————————————————————————————————————————————————————————————- You can reach out to this dude myco.spor on Instagram I ordered from . He sells psychedelics discreetly, hove Mushroom Embryos, shrooms, Dmt , Lsd and more 🍄💯 he could direct you also on how to microdos 🤩🍄💯

  7. If you take SSRIs then really consider if this is something for you. There are serious risks when combining. And if you have schizophrenia it can trigger a psychotic episode. It's best to join a forum or page and look at all feedback. But it can definitely help with mood if you aren't on meds.

  8. Yesterday I ate 4g of mushrooms that I grew and it was the most incredible 9 hours of my life! After the flying through dimensions wore off I felt reset and something in my brain had been activated that made me feel extroverted and clear🍄🌍❤️

  9. I APPRECIATE THE RECOMMENDATIONS I SAW HERE HE'S TRULY AS GOOD AS YOU'LL SAY ——————————————————————————————————————————————————————————————————————————————————————————————————————————- You can reach out to this dude myco.spor on Instagram I ordered from . He sells psychedelics discreetly, hove Mushroom Embryos, shrooms, Dmt , Lsd and more 🍄💯 he could direct you also on how to microdosing

  10. I APPRECIATE THE RECOMMENDATIONS I SAW HERE HE'S TRULY AS GOOD AS YOU'LL SAY ——————————————————————————————————————————————————————————————————————————————————————————————————————————- You can reach out to this dude myco.spor on Instagram I ordered from . He sells psychedelics discreetly, hove Mushroom Embryos, shrooms, Dmt , Lsd and more 🍄💯 he could direct you also on how to microdosing

  11. first off i did tons of research and went into it with a great mindset, i just had my first small light trip a week ago and holy shit is there power in this medicine! for lack of a better explanation i refocused my priorities and started doing things i needed to be doing while focusing on taking better care of my health. its not a magical cure all but it is a brain/mindset intensifier. you get out what you put in. wisdom states nature provides what you need and boy is that true.

  12. I can't believe the statement here
    Mushrooms are very dangerous and have sever life lasting consequences
    Mushrooms are nor safe
    Not for anyone especially people wit a medical condition

  13. I used it once as a last ditch method before offing myself and it worked wonders! It is thankfully available in Netherlands and some US states, so kinda available to everyone. I don't feel the need to use it again and it is true that I was noticing things that I stopped ages ago, following the same loop of depression. Than I took the stuff and I did many things for the first time. Took the first full breath of air, and so on. I was always emphatic, that didn't change, only I understood the point of views I discarded before and learn that the world is AS IS and it is wrong to just EXPECT anything out of anyone. They are as they are. If you can talk things out, cool, if not – let it go.

  14. My experience with psilocybin is basically the opposite of what a lot of people are describing. It made me ruminate about my past more and made me more sentimental. It progressively made me more depressed until I stopped taking it.

  15. Hallucinogens in nature were catalysts to the rapid evolving of our squishy noggin' noodles…
    …according to the metallic wormhole guardians who accompanied me on a sweet tour of the other realms and eased my transition back thru the vapidity of this Idiocratic nightmare

  16. If its truly good for us we won't be allowed to take it.

    The 1% wouldn't thrive if we were to.

    Big pharma and high status society would wipe out due to psilocybin ultimately breaking down all our indoctrinated fear factors.

    If we were all truly happy and content we wouldn't be programmable for a 9-5 society that boats the bank accounts of the richest in the world.

  17. The only thing I would add to this is that you need a good sized dose to get the "reset" If you chicken out and only do 2 grams, it's not all that worth it. You need your mind temporarily blown. It's worth it in the end, I know from experience.

  18. In micro doses I'm sure it could. But don't eat a bunch of mushrooms for an extended period of time and expect these results, quite the opposite in fact. I ate them multiple times a week for about 3 months one summer; my brain chemistry was screwed up for about 6 months after that, feelings ranging from none at all (no apathy/empathy) to feelings of depression. Use psyli wisely.

  19. This has been known FOR YEARS. I had OCD as a teen which was treated with antidepressants. Even BACK THEN in 1999, the internet forums told me that magic mushrooms could clear it for YEARS, if not for life. But HERE WE ARE, STILL fiddling around…. these drug companies DON'T WANT a one dose solution….

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