DNA Replication (Updated)



Explore the steps of DNA replication, the enzymes involved, and the difference between the leading and lagging strand! This video is an update from our old DNA replication video with nearly the same script but added detail and improved art! See table of contents by expanding details.

Table of Contents:
00:00 Intro
0:11 Why do you need DNA replication?
0:27 Where and when?
1:12 Introducing key player enzymes
2:48 Initial steps of DNA Replication
4:04 Explaining 5′ to 3′ and 3′ to 5′
5:09 Showing leading and lagging strands in DNA replication

Video has a handout here: http://www.amoebasisters.com/handouts

Factual Reference:
OpenStax, Biology. OpenStax CNX. May 8, 2019 http://cnx.org/contents/185cbf87-c72e-48f5-b51e-f14f21b5eabd@11.10.

***Further Reading Suggestions***

-More info about prokaryote vs. eukaryote DNA Replication? (Which video doesn’t go into) Check out the bottom of this page of the peer-reviewed, FREE OpenStax testbook: https://cnx.org/contents/GFy_h8cu@11.10:2l3nsfJK@5/DNA-Replication-in-Eukaryotes

-More detail about DNA replication, including the different types of polymerase? Check out this page of the peer-reviewed, FREE OpenStax textbook: https://cnx.org/contents/GFy_h8cu@11.10:NEk9ll-3@8/DNA-Replication-in-Prokaryotes

-Check out this science paper that details how cancer drugs can work to stop DNA replication in cancer cells. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797825/

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Our intro music designed and performed by Jeremiah Cheshire.

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33 thoughts on “DNA Replication (Updated)

  1. But the thing I don't understand is, how did they know all of this? Am I expected to just sit there and absorb this info as if it was factual with no means of understanding how we came to this? Any proof at all or anything that can be seen?

  2. The funny illustrations make these videos so enjoyable whilst learning difficult topics. Thanks for making learning fun again.

  3. UPDATE: We have videos dubbed in Spanish and Portuguese using an artificial voice via https://aloud.area120.google.com to increase accessibility. See our Amoeba Sisters en Español channel https://www.youtube.com/channel/UC1Njo3LBy53cOPngz6ArV8Q and Amoeba Sisters em Português https://www.youtube.com/channel/UCYTQPX2X_mXe0ZMPi0fXxbg Want to help translate our subtitles in any language? Learn more here https://www.amoebasisters.com/pinkys-ed-tech-favorites/community-contributed-subtitles

    We hope you like our newly updated DNA replication vid! So what's different? You will find the script to be almost the same, except with a little more detail: we included topoisomerase activity and better explained leading and lagging strands. (Again, remember, there is still much detail to explore beyond this video!) Our art has also improved as we continue to practice and no MS Paint this time ha! You can see our milestones here: https://www.amoebasisters.com/milestones.html Also, no worries, we try to not delete old videos. The old DNA replication video, if you prefer it, is still here: https://youtu.be/5qSrmeiWsuc

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