In this UCSF Medical Grand Rounds (July 30, 2020), we get updates on three key issues in the Covid-19 pandemic. Chaz Langelier reviews testing, including test shortages, false positives and negatives, and the meaning of persistent PCR positivity. Annie Luetkemeyer offers an update on treatments, including remdesivir, dexamethasone, convalescent plasma and antibodies, interferon, hydroxychloroquine, and the prospects for oral therapies. Finally, Joel Ernst reviews the latest information about vaccines, including trials of the Moderna and Oxford vaccines, our growing understanding of Covid-19 immunity, the ethics of challenge trials, and determination of priority groups once a vaccine is approved. The session is hosted by UCSF Department of Medicine chair Bob Wachter.

Program
Bob Wachter: Introduction
00:05:30 – Testing: Chaz Langelier, Assistant Professor of Medicine, Division of Infectious Diseases at UCSF Health
00:23:35 – Q&A
00:27:20 – Treatments: Annie Luetkemeyer, Professor of Medicine, Division of HIV, ID and Global Medicine at ZSFG
00:48:36 – Q&A
00:52:43 – Vaccines: Joel Ernst, Professor of Medicine and Chief of Division of Experimental Medicine at ZSFG
01:12:30 – Q&A
01:15:18 – Panel Discussion
01:28:43 – Bob Wachter: Closing

Read the UCSF Magazine here: https://www.ucsf.edu/magazine

See previous Covid-19 Medical Grand Rounds:
• July 23: Covid-19: Reports of New Surges from Miami, Atlanta, Houston, and UCSF

• July 16: How the Virus Gets in and How to Block It: Aerosols, Droplets, Masks, Face Shields, and More

• July 9: The State of the Pandemic, Opening the Schools, and the Outbreak at San Quentin State Prison

• June 25: Special Presentation: An Interview with John Barry, Author of the Bestselling Book, The Great Influenza: The Story of the Deadliest Pandemic in History

See all UCSF Covid-19 grand rounds, which have been viewed more than 600,000 times, here: https://medicine.ucsf.edu/covid-19-news-coverage

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